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20S-Proteasome (20S-PSM), Human, ELISA Kit




 

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Product Code: CED321HU


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Product Details
 
Product Code:CED321Hu
Product:20S-Proteasome (20S-PSM), Human, ELISA Kit
Background:The number and diversity of subunits contained in the 20S core particle depends on the organism; the number of distinct and specialized subunits is larger in multicellular than unicellular organisms and larger in eukaryotes than in prokaryotes. All 20S particles consist of four stacked heptameric ring structures that are themselves composed of two different types of subunits; ? subunits are structural in nature, whereas ? subunits are predominantly catalytic. The outer two rings in the stack consist of seven ? subunits each, which serve as docking domains for the regulatory particles and the alpha subunits N-termini form a gate that blocks unregulated access of substrates to the interior cavity. The inner two rings each consist of seven ? subunits and contain the protease active sites that perform the proteolysis reactions. The size of the proteasome is relatively conserved and is about 150 angstroms () by 115 .
Synonyms:CP, 20SPSM, 20S Core Particle
Species:Human
Detection range:617.3-50,000ng/mL
Sensitivity:225.6ng/mL
Configuration:12x8
Intended Use: For Research Use Only
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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