Home > Products > Proteins > Recombinant Protein >

4-1BB Ligand, Human, Recombinant




 

Our Price: $99.00

Product Code: 28-10068


Size*:
5 µg
20 µg [Add $100.00]
1 mg [Add $3,000.00]

Qty:
Product Details
 
Product Code:28-10068
Product:4-1BB Ligand, Human, Recombinant
Description:4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.
Synonyms:TNFSF9, CD137L
AA Sequence:MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE
Source:E. Coli
Purity:98%
Biological Activity:Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED 50 for this effect is 5-10 ng/ml.
Please Note: Results may vary with PBMC donors.
Cross Reactivity:NULL
Endotoxin Level:Endotoxin level is <0.1 ng/ug of protein (<1EU/ug).
Protein Content:Verified by UV Spectroscopy and/or SDS-PAGE gel.
Authenticity:Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Interest Fields:Angiogenesis/Cardiovascular, Apoptosis, Immune System, TNF Superfamily, Transplantation
Storage:Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Share your knowledge of this product. Be the first to write a review »