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ABCG2 Polyclonal Antibody




 

Our Price: $220.00

Product Code: A1370


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Product Details
 
Product CodeA1370
Product:ABCG2 Polyclonal Antibody
Background:The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Category:Polyclonal Antibody
Species:Rabbit
Synonyms:MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, MXR-1, CDw338, UAQTL1, EST157481,
Immunogen:A synthetic Peptide of human ABCG2
Isotype:IgG
Molecular Weight:72kDa
Purity:Affinity purification
Form:Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reactivity:Human
Applications:WB, IHC, FC
Working Dilutions:WB 1:500 - 1:1000
IHC 1:20 - 1:50
FC 1:20 - 1:50
GeneID:9429
SwissProt:Q9UNQ0
Storage:Store at 4C. Avoid freeze/thaw cycles.
Image Description:Western blot analysis of extracts of various cell lines, using ABCG2 antibody.
Research Area:Cancer, Stem cells, Neural Stem Cells, Neuroscience, Metabolism,
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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