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ATG5 Polyclonal Antibody




 

Our Price: $130.00

Product Code: A11427


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Product Details
 
Product CodeA11427
Product:ATG5 Polyclonal Antibody
Background:Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1,2). Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer (3). The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles (4-6). This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10 (7,8).
Category:Polyclonal Antibody
Species:Rabbit
Synonyms:ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5 ,
Immunogen:Recombinant protein of human ATG5
Isotype:IgG
Molecular Weight:32kDa
Purity:Affinity purification
Form:Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reactivity:Human, Mouse, Rat
Applications:WB, IHC
Working Dilutions:WB 1:500 - 1:2000
IHC 1:50 - 1:100
GeneID:9474
SwissProt:Q9H1Y0
Storage:Store at -20C. Avoid freeze/thaw cycles.
Image Description:Western blot analysis of extracts of various cell lines, using ATG5 antibody.|Immunohistochemistry of paraffin-embedded human stomach using ATG5 antibody at dilution of 1:100 (x40 lens).|Immunohistochemistry of paraffin-embedded rat heart using ATG5 antibody at dilution of 1:100 (x40 lens).|Immunohistochemistry of paraffin-embedded human lung using ATG5 antibody at dilution of 1:100 (x40 lens).
Research Area:Cancer, Apoptosis, Autophagy pathway, Cardiovascular, Cell Biology, Metabolism,
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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