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Anti-Adeno-associated virus (AAV), VP 1




 

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Product Code: 03-61056


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Product Details
 
Product Code:03-61056
Product:Anti-Adeno-associated virus (AAV), VP 1
Description:Mouse Monoclonal Antibody to Adeno-associated virus (AAV), VP 1. A1 reacts with VP1 of adeno-associated virus. A1 reacts with VP1 of AAV-2; weak cross-reaction with serotypes 1, 3, 4, 5, 6. In immunoprecipitation, an occasional reaction with a non-AAV-derived protein is found.
Category:Mouse monoclonal
Clone:A1
Ig Subtype:IgG2a
Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models
Synonyms:AAV2
Immunogen:Adeno-associated virus capsid proteins and virus particles
Form:Purified (Protein A), in PBS containing 1% BSA and 0.1% sodium-azide
Reactivity:AAV-2, found in human and monkey. Weak cross-reaction with serotypes 1, 3, 4, 5 and 6
Specificity:Epitope mapping experiments (Wobus et al., see below) identified aa123 to aa131 of VP1 capsid protein as the specific binding region. In immunoprecipitation, an occasional reaction with a non-AAV-derived protein is found
Applications:ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Immunoblotting
Working Dilution:1:5 - 1:10 for immunohistochemistry
Storage:2-8C for immediate use, or at -20C (aliquot)
References:
  • Wistuba, A. et al.(1997) J. of Virology 71: 1341-1352
  • Wobus,CE. et al. (2000) J. Virol 74 (19): 9281-9292
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

Average Rating: 5 of 5 Total Reviews: 1 Write a review »

  0 of 0 people found the following review helpful:
 
Good VP1 antibody for IHC May 10, 2016
Reviewer: Dr. James Marshall from San Diego, United States  
This antibody works well in IHC for detecting VP1 of AAV.

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