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Anti-Adeno-associated virus (AAV), VP1, VP2, VP3

Anti-Adeno-associated virus (AAV), VP1, VP2, VP3


Our Price: $139.00

Product Code: 03-61057

200 ┬Ál

Product Details
Product Code:03-61057
Product:Anti-Adeno-associated virus (AAV), VP1, VP2, VP3
Description:Mouse Monoclonal Antibody to Adeno-associated virus (AAV), VP 1 & VP2. A69 reacts with VP 1 and VP 2 of adeno-associated virus which are highly enriched in the nucleus. Recognizes AAV-2 viral capsid proteins VP1 and VP2, which are highly enriched in the nucleus. Weak cross-reaction with serogroups 1, 3, and 6.
Category:Mouse monoclonal
Ig Subtype:IgG1
Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models
Immunogen:Adeno-associated virus capsid proteins and virus particles
Form:Purified (Protein A), in PBS containing 1% BSA and 0.1% sodium-azide
Reactivity:AAV-2, human, monkey. Weak cross reaction with serotypes 1, 3 and 6
Specificity:Epitope mapping experiments (Wobus et al.) identified aa 169 to aa 184 of VP2 and (with reduced intensity) aa 123 to aa136 of VP1 capsid proteins as the specific binding region.
Applications:Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Immunoblotting
Working Dilution:1:10 for immunohistochemistry
Storage:2-8C for immediate use, or at -20C (aliquot)
  • Wistuba, A. et al. (1995) J. Virol. 69: 5311-5319
  • Wistuba, A. et al. (1997) J. Virol. 71: 1341-1352
  • Wobus,CE. et al. (2000) J. Virol 74 (19): 9281-9292
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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