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Bovine CAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B) ELISA Kit

Bovine CAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B) ELISA Kit


 
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Product Code: AE25986BO


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Product Details
 
Product CodeAE25986BO
Product:Bovine CAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B) ELISA Kit
Species:Bovine (Bos taurus, Cattle)
Background:The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKAR2b is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity.
Abbreviation:PRKAR2B
Synonyms:PRKAR2, RII-BETA, H_RG363E19.2|WUGSC:H_RG363E19.2|cAMP-dependent protein kinase type II-beta regulatory chain|cAMP-dependent protein kinase, regulatory subunit beta 2
Sample Types:Serum, Plasma, Other biological fluids
Detection Method:Sandwich
Analysis Method:Quantitive
UniProt ID:P31322
Intended Use:For Research Use Only
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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