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25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1), Human, ELISA Kit

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1), Human, CSB-EL006406HU | ARP American Research Products, Inc.

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Product Code: CSB-EL006406HU

48T [Subtract -$200.00]
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Product Details Protocol
Product Code: CSB-EL006406HU
Product Name:25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1), Human, ELISA Kit
Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.
Antigen Name:Cytochrome P450, family 27, subfamily B, polypeptide 1
Synonyms:CP2B, CYP1, CYP1alpha, CYP27B, P450c1, PDDR, VDD1, VDDR, VDDRI, VDR1alpha(OH)ase, 25 hydroxyvitamin D3-1-alpha hydroxylase, 25-Hydroxyvitamin D3 1alpha-hydroxylase, 25-OHD-1 alpha-hydroxylase, 25-hydr
Sample Types:Serum, Plasma, Tissue Homogenates, Cell Lysates
Detection Range:31.25 pg/ml-2000 pg/ml
Sensitivity:7.81 pg/ml
Intended Use: For Research Use Only.

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