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Polyclonal antibodies (PAbs) are powerful biological tools that are used in the analysis of antigens in a wide variety of research and in vitro diagnostic applications. Traditionally, polyclonal antibodies are raised in large animals such as goats and rabbits. The immunized animal produces an antibody response that is heterogeneous in nature and the serum harvested recognizes multiple antigenic epitopes. Polyclonal antibodies can be generated more rapidly than monoclonal antibodies (MAbs) and consequently a vast number of polyclonal antibodies have been developed against a wide range of biological targets. In recent years, the use of affinity purification has improved the quality and performance of polyclonal antibodies. Like Monoclonal antibodies, PAbs are used in a wide variety of applications including western blotting, Enzyme linked immunosorbent assays (ELISA), immunohistology and immunoprecipitation techniques. Polyclonal antibodies are more stable than MAbs over a broad pH and are therefore more suitable for pH sensitive applications.

ARP American Research Products provides an extensive range of internationally recognised polyclonal antibodies. The product range includes high quality antibodies, designed for research use, against biological targets that are of potential diagnostic and therapeutic interest.

Polyclonal antibodies recognizing complement components

The complement system consists of a specific group of proteins that play a pivotal role in the innate immune response, inflammation and homeostasis. In response to the recognition of a potential pathogen, inactive complement proteins interact with each other in an enzymatic cascade and become sequentially activated. Protein fragments are generated during this process that act as chemo-attractants, adhesion molecules and opsonins. The complement system can be activated via three different pathways 1) Classical pathway 2) alternative pathway 3) Mannose binding lectin pathway.

ARP American Research Products supplies a wide range of polyclonal antibodies that recognize key components of the complement system including C1q and Cd4.

· 12-5000 Rabbit anti human C4d

· 12-5050 Rabbit anti human C4d: Ready-to-use

· 21-1131 Goat anti C1q conjugated to FITC


Polyclonal anti p62 protein

The p62 protein, also known as sequestosome 1, is encoded by the SQSTM1 gene. It is an adaptor protein that binds ubiquitin and is involved in bone remodelling and various cellular processes. P62 also acts as an autophagy receptor that is required for the formation and degradation of ubiquitin.

ARP supplies a range of polyclonal antibodies recognizing the p62 protein including a guinea pig polyclonal against the C-terminal region of p62.

· 16-RB62 Rabbit anti p62

· 03-GP62-C Guinea pig anti p62 (C-terminal)

Polyclonal antibodies recognizing Adeno-associated virus (AAV)

Adeno-associated viruses A(AAV), from the parvovirus family, are small single-stranded DNA viruses that affect humans and some additional primate species. AAV are currently considered to be non-pathogenic and most people infected with AAV only develop a mild immune response. Adeno-associated viruses carry genes into both dividing and quiescent cells where they can insert genetic information into the host genome These characteristics of AAV have been exploited for gene therapy and AAV virus have been engineered to carry therapeutic genes into host cells. A range of polyclonal antibodies are available from ARP which recognize intact AAV particles and capsid proteins VP1, VP2 and VP3.

· 03-61084 Rabbit anti Adeno-associated virus (AAV) VP1, VP2, VP3

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A11583
A1BG Polyclonal Antibody

Our Price: $130.00
A11584
A1BG Polyclonal Antibody

Our Price: $130.00
A1573
A2M Polyclonal Antibody

Our Price: $130.00
A8817
A4GALT Polyclonal Antibody

Our Price: $130.00
A12366
A4GNT Polyclonal Antibody

Our Price: $130.00
A6427
AAAS Polyclonal Antibody

Our Price: $130.00
A10365
AADAC Polyclonal Antibody

Our Price: $130.00
A3283
AAMP Polyclonal Antibody

Our Price: $130.00
A11850
AANAT Polyclonal Antibody

Our Price: $220.00
A11846
AARS Polyclonal Antibody

Our Price: $220.00
A7864
AARS Polyclonal Antibody

Our Price: $130.00
A7826
AARS2 Polyclonal Antibody

Our Price: $130.00
A5299
ABAT Polyclonal Antibody

Our Price: $130.00
A7228
ABCA1 Polyclonal Antibody

Our Price: $130.00
A9436
ABCA2 Polyclonal Antibody

Our Price: $220.00
A6862
ABCA3 Polyclonal Antibody

Our Price: $130.00
A10556
ABCA4 Polyclonal Antibody

Our Price: $130.00
A3191
ABCA6 Polyclonal Antibody

Our Price: $130.00
A11747
ABCB1 Polyclonal Antibody

Our Price: $130.00
A11758
ABCB1 Polyclonal Antibody

Our Price: $130.00
   
 
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