4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease.
Synonyms: Tumor necrosis factor ligand superfamily member 9(TNFSF9), 4-1BBL, CD137L

4-1BB Ligand, human (TNFSF9, 71-254aa, His-tagged). Recombinant, E. coli. Purified. Size: 20ug