14-3-3 η (K81) Polyclonal Antibody

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BS2384
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Antibodies, Polyclonal Antibodies, Bioworlde
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Product Name 14-3-3 η (K81) Polyclonal Antibody
Reactivity Human, Mouse, Rat
Applications IF, IHC, WB
Background 14-3-3 eta (YWHAH) belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine or phosphothreonine-containing proteins. YWHAH is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners and binding generally results in the modulation of the activity of the binding partner. The YWHAH gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
Concentration 1 mg/ml
Form Liquid, in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Host Rabbit
Immunogen Synthetic peptide, corresponding to amino acids 50-100 of Human 14-3-3 ?
Intended Use For Research Use Only
Molecular Weight ~ 28 kDa
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity 14-3-3 ? (K81) polyclonal antibody detects endogenous levels of 14-3-3 ? protein.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
SwissProt Q04917
Synonyms 14-3-3 protein eta, Protein AS1, YWHAH, YWHA1, 1433F
Working Dilutions WB: 1:500~1:1000; IHC: 1:50~1:200; IF: 1:50~1:200

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