14-3-3 tau, 1-245aa, Human, Recombinant

Proteins, Recombinant
More Information
Product Name 14-3-3 tau, 1-245aa, Human, Recombinant
Background The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. Recombinant human YWHAQ was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Synonyms YWHAQ, 1C5, HS1, 14-3-3 tau, Tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide, tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, theta polypeptide 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14 3 3 tau, 14 3 3 theta, KCIP1, Protein HS1, Protein kinase C inhibitor protein 1, tyr3/trp5 monooxygenase activation protein, theta, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide.
Host E.coli
Tag His-tag
Molecular Weight 57 kDa ( 511 aa), confirmed by MALDI-TOF.
Form Liquid, in 20mM Tris pH 8.0, 0.1mM DTT, 10%glycerol
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_006817
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Liu YC, et al. (1996) J Biol Chem; 271: 14591-5
Xiao B, et al. (1995) Nature, 376; 188-191

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