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14-3-3 zeta, 1-245aa, Human, His-tagged, Recombinant, E.coli




 

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Product Code: 01-2057ZE


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20 µg
100 µg [Add $190.00]
0.5 mg [Add $670.00]

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Product Details
 
Product Code:01-2057ZE
Product:14-3-3 zeta, 1-245aa, Human, His-tagged, Recombinant, E.coli
Description:The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Recombinant human YWHAZ, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms:YWHAZ, KCIP-1, MGC111427, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, 14-3-3 zeta , Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 14 3 3 protein zeta/delta, KCIP1, Phospholipase A2, Protein kinase C inhibitor protein 1, Tyr-3/Trp-5 monooxygenase Activation protein, Zeta, Tyr3/Trp5 monooxygenase Activation protein, Zeta
NCBI Number:NP_ 663723
Antigen Species:Human
Applications:SDS-PAGE
Form:Liquid in Phosphate Buffered Saline pH7.4
Concentration:1 mg/ml (determined by Bradford assay)
Purity:> 95% by SDS - PAGE
Molecular Weight:32 kDa (245 aa), confirmed by MALDI-TOF.
Amino Acid Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMDK NELVQKAKLA EQAERYDDMA ACMKSVTEQG AELSNEERNL LSVAYKNVVG ARRSSWRVVS SIEQKTEGAE KKQQMAREYR EKIETELRDI CNDVLSLLEK FLIPNASQAE SKVFYLKMKG DYYRYLAEVA AGDDKKGIVD QSQQAYQEAF EISKKEMQPT HPIRLGLALN FSVFYYEILN SPEKACSLAK TAFDEAIAEL DTLSEESYKD STLIMQLLRD NLTLWTSDTQ GDEAEAGEGG EN
Gene Category:Signal Transduction
Storage:Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References:
  • Gannon-Murakami L., et al. (2002) J Biol Chem. 277(26): 23116-23122
  • Li FQ., et al. (2008) J Cell Biol. 181(7):1141-54
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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