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AAV-2 Titration ELISA




 

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Product Code: PRATV


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96T

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Product Code:PRATV
Product:AAV-2 Titration ELISA
Description:Enzyme Immunoassay for the Quantitative Determination of AAV Serotype 2 Particles in Cell Culture Supernatants and Purified Virus Preparations.
Background:Adeno-associated virus (AAV) is a non pathogenic ssDNA virus that is a topic of intense study in gene therapy. The virus transduces a wide variety of dividing and non-dividing cells showing long-term gene expression with no cellular immune response. AAV has been used in several clinical trials (e.g. FIX, CFTR, Parkinson's, Canavan disease) showing no serious vector-related adverse effects. Methods for the characterisation of A A V preparations currently include titration ELISA, real- time PCR, DNA dot blot, determination of transducing units, infectious center assay, SDS- PAGE or electron microscopy.

Immunotitration by ARP's AAV 2 Titration ELISA offers a fast, sensitive and reproducible method for titration of intact AAV 2 wt virions, AAV 2 recombinant virions or assembled and intact empty AAV 2 capsids.
Storage:2-8C
Intended Use:For Research Use Only
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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