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ABCA4 Polyclonal Antibody




 

Our Price: $130.00

Product Code: A10556


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Product Details
 
Product CodeA10556
Product:ABCA4 Polyclonal Antibody
Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
Category:Polyclonal Antibody
Species:Rabbit
Synonyms:FFM, RMP, ABCR, RP19, STGD, ABC10, ARMD2, CORD3, STGD1,
Immunogen:Recombinant protein of human ABCA4
Isotype:IgG
Molecular Weight:256kDa
Purity:Affinity purification
Form:Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reactivity:Human, Mouse, Rat
Applications:WB
Working Dilutions:WB 1:1000 - 1:2000
GeneID:24
SwissProt:P78363
Storage:Store at -20C. Avoid freeze/thaw cycles.
Image Description:Western blot analysis of extracts of various cells, using ABCA4 antibody.
Research Area:Neuroscience,
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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