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ABCB1 Polyclonal Antibody




 

Our Price: $130.00

Product Code: A11747


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Product Details
 
Product CodeA11747
Product:ABCB1 Polyclonal Antibody
Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Category:Polyclonal Antibody
Species:Rabbit
Synonyms:CLCS, MDR1, P-GP, PGY1, ABC20, CD243, GP170
Immunogen:A synthetic peptide of human ABCB1
Isotype:IgG
Molecular Weight:141 kDa
Purity:Affinity purification
Form:Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reactivity:Human
Applications:WB
Working Dilutions:WB 1:500 - 1:2000
GeneID:5243
SwissProt:P08183
Storage:Store at -20C. Avoid freeze/thaw cycles.
Image Description:Western blot analysis of extracts of various cell lines, using ABCB1 antibody.
Research Area:Cancer, Stem cells, Metabolism,
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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