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Amyloid Precursor Protein (APP), Human, CLIA Kit




 

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Product Code: SCB020HU


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Product Details
 
Product Code:SCB020Hu
Product Name:Amyloid Precursor Protein (APP), Human, CLIA Kit
Host:Human
Synonyms:AAA, ABeta, ABPP, AD1, APPI, CVAP, PN2, CTFgamma, Peptidase Nexin-II Alzheimer Disease, Peptidase Nexin-II, Amyloid Beta (A4)Precursor Protein
Background: Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation and neural plasticity. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates amyloid beta (A?), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.Several alternative splicing isoforms of APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.
Detection Range:78-5,000pg/mL
Sensitivity:28pg/mL
Configuration:12x8
Intended Use:For Research Use Only.
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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