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Anti-Adeno-Associated Virus (AAV), Rep Protein

Anti-Adeno-Associated Virus (AAV), Rep Protein


Our Price: $139.00

Product Code: 03-61073

200 ┬Ál

Product Details
Product Code:03-61073
Product:Anti-Adeno-Associated Virus (AAV), Rep Protein
Description:Mouse Monoclonal Antibody to Adeno-Associated Virus (AAV), Rep Protein. Recognizes AAV replicase proteins Rep78 and Rep52 in human AAV-2-infected cells, no reaction with Rep68 and Rep40. Weak cross-reaction with AAV-serotype 3. The Rep proteins are expressed in different concentrations during infection.
Category:Mouse monoclonal
Ig Subtype:IgG1
Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models
Immunogen:Rec.AAV-2 Rep 78 protein, N-terminally truncated by 171 aa
Form:Purified (Protein A), in PBS containing 1% BSA and 0.1% sodium-azide
Reactivity:AAV-2, found in human
Specificity:Mab 76.3 reacts with Rep proteins (Rep78 and Rep52) of human AAV-2 infected cells, does not react with Rep68 and Rep40. The Rep proteins are expressed in different concentrations during infection.
Applications:Immunoprecipitation, Immunofluorescence microscopy
Working Dilution:1:10 for immunofluorescence microscopy
Storage:2-8C for immediate use, or at -20C (aliquot)
  • Wobus,CE. et al. (2000) J. Virol 74 (19): 9281-9292
  • Wistuba, A. et al. (1995) J. Virol. 69: 5311-5319
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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