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Rabbit anti human C4D antibody :: Anti-C4d (12-5000)

C4d Kidney IHC

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Our Price: $339.00

Product Code: 12-5000

250 µl

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Rabbit anti human C4D antibody :: Anti-C4d (12-5000)

Polyclonal antibody against human C4d

Product Code: 12-5000

Anti-C4d Antibody

Description: Rabbit polyclonal Antibody to human C4d
Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluste exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene.
Category: Rabbit Polyclonal
Immunogen: Synthetic peptide specific for human C4d conjugated to KLH (keyhole limpet hemocyanin)
Form: Affinity Purified IgG, in PBS, containing Stabilizer and 0.02% sodium aide
Antigen Recognized in Species: Human, tested so far
Specificity: Human C4d
Applications: Immunohistochemistry, suitable for frozen section and paraffin embedded tissue. Pretreatment of sample is highly recommended for antigen retrieval.
Working Dilution: min.1: 50 (see protocol)
Storage: 2-8C for immediate use, or at -20C (aliquot). AVOID repeated freezing and thawing
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

Average Rating: 5 of 5 Total Reviews: 1 Write a review »

  0 of 0 people found the following review helpful:
great antibody September 15, 2016
Reviewer: Renata BK from Cleveland, OH United States  
C4d staining is very good with great consistency. Highly recommended

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