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ENPP7 Polyclonal Antibody

ENPP7 Polyclonal Antibody


 

Our Price: $130.00

Product Code: A2912


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50 µl
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Product Details
 
Product CodeA2912
Product:ENPP7 Polyclonal Antibody
Background:Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) also known as alkaline sphingomyelin phosphodiesterase (Alk-SMase) or intestinal alkaline sphingomyelinase is an enzyme that in humans is encoded by the ENPP7 gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
Category:Polyclonal Antibody
Species:Rabbit
Synonyms:ALK-SMase,
Immunogen:A synthetic peptide of human ENPP7
Isotype:IgG
Molecular Weight:52kDa
Purity:Affinity purification
Form:Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reactivity:Human
Applications:WB, IHC
Working Dilutions:WB 1:500 - 1:2000
IHC 1:50 - 1:200
GeneID:339221
SwissProt:Q6UWV6
Storage:Store at -20C. Avoid freeze/thaw cycles.
Image Description:Western blot analysis of extracts of HepG2 cell line, using ENPP7 antibody.|Immunohistochemistry of paraffin-embedded human cervical cancer tissue using ENPP7 antibody.
Research Area:Cancer, Cell cycle, Cell Biology, Epigenetics,
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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