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Enolase, Non Neuronal (NNE), Human, CLIA Kit

Enolase, Non Neuronal (NNE), Human, CLIA Kit


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Product Code: SCB449HU


Product Details
Product Code:SCB449Hu
Product Name:Enolase, Non Neuronal (NNE), Human, CLIA Kit
Synonyms:ENO1, ENO1L1, MBP-1, MPB1, PPH, Alpha Enolase
Background: Enolase 1, more commonly known as?-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase. It is a homodimer composed of 2 alpha subunits. Its gene, the ENO1, also encodes the Myc-binding protein-1(MBP1), which downregulates the activity of c-myc protooncogene. Alpha-enolase is the longer form (48 kDa) localized in both cytoplasm and nuclei, while MBP1 is shorter (37 kDa) and is found mostly in the nuclei.Alpha-enolase has been identified as an autoantigen in Hashimotos encephalopathy. Single studies have also identified it as an autoantigen associated with severe asthma and a putative target antigen of anti-endothelial cell antibody in Beh├žets disease.Reduced expression of the enzyme has been found in the corneas of people suffering from keratoconus.
Detection Range:0.312-20ng/mL
Intended Use:For Research Use Only.
This product is sold for laboratory research use or further manufacturing only and should not be used for human therapeutic or diagnostic applications. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process.

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