AAV-8 Titration ELISA

Category: Anti-AAV Products
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PRAAV8
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Product Name AAV-8 Titration ELISA
Description Adeno-associated virus (AAV) is a non pathogenic ssDNA virus that is a topic of intense study in gene therapy. The virus transduces a wide variety of dividing and non-dividing cells showing long-term gene expression with no cellular immune response. AAV has been used in several clinical trials (e.g. FIX, CFTR, Parkinson’s disease, Canavan disease) showing no serious vector-related adverse effects. Methods for the characterisation of AAV preparations currently include titration ELISA, realtime PCR, DNA dot blot, determination of transducing units, infectious center assay, SDSPAGE or electron microscopy. Immunotitration by ARP's AAV8 Titration ELISA offers a fast, sensitive and reproducible method for titration of intact AAV8 wt virions, AAV8 recombinant virions or assembled and intact empty AAV8 capsids. Enzyme Immunoassay for the Quantitative Determination of AAV Serotype 8 Particles in Cell Culture Supernatants and Purified Virus Preparations
Storage 2-8C
Supplier Progen

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