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|Product Name||ACADM, 26-421aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MKANRQREPG LGFSFEFTEQ QKEFQATARK FAREEIIPVA AEYDKTGEYP VPLIRRAWEL GLMNTHIPEN CGGLGLGTFD ACLISEELAY GCTGVQTAIE GNSLGQMPII IAGNDQQKKK YLGRMTEEPL MCAYCVTEPG AGSDVAGIKT KAEKKGDEYI INGQKMWITN GGKANWYFLL ARSDPDPKAP ANKAFTGFIV EADTPGIQIG RKELNMGQRC SDTRGIVFED VKVPKENVLI GDGAGFKVAM GAFDKTRPVV AAGAVGLAQR ALDEATKYAL ERKTFGKLLV EHQAISFMLA EMAMKVELAR MSYQRAAWEV DSGRRNTYYA SIAKAFAGDI ANQLATDAVQ ILGGNGFNTE YPVEKLMRDA KIYQIYEGTS QIQRLIVARE HIDKYKN|
|Background||ACADM, also known as acyl-Coenzyme A dehydrogenase is an enzyme that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. It is essential for converting these particular fatty acids to energy, especially during periods without food (fasting). This protein functions in mitochondria, the energy-producing centers within cells. It is found in the mitochondria of several types of tissues, particularly the liver. Recombinant human ACADM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques|
|Concentration||0.25mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl|
|Intended Use||For Research Use Only|
|Molecular Weight||22.8kDa (201aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_000007|
|Purity||> 90% by SDS-PAGE|
|References||Gregersen N., et al. (2001) Hum Mutat. 18(3):169-89.|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||ACAD1, CAD, MCADH, Medium-chain specific acyl-CoA dehydrogenase, ACAD 1, Acyl Coenzyme A Dehydrogenase, Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain, C4 to C12 Straight Chain, FLJ18227, FLJ93013, FLJ99884, MCAD, Medium chain acyl CoA dehydrogenase, Medium chain fatty acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase mitochondrial|
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