| Product Name | ACPP, 33-386aa, Human, Baculovirus (Bioactivity Validated) |
|---|---|
| Description | ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms |
Prostatic acid phosphatase isoform PAP , ACPP, 5-NT, ACP-3, ACP3, 5-NT, 5-nucleotidase Acid phosphatase prostate, ACP 3, ACP3, acpP Ecto-5-nucleotidase, PAP, PPAP_HUMAN Prostatic acid phosphatase, Thiamine monophosphatase, TMPase |
| Host | Baculovirus |
| Molecular Weight |
41.6kDa (380aa) 40-57kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence |
KELKFVTLVF RHGDRSPIDT FPTDPIKESS WPQGFGQLTQ LGMEQHYELG EYIRKRYRKF LNESYKHEQV YIRSTDVDRT LMSAMTNLAA LFPPEGVSIW NPILLWQPIP VHTVPLSEDQ LLYLPFRNCP RFQELESETL KSEEFQKRLH PYKDFIATLG KLSGLHGQDL FGIWSKVYDP LYCESVHNFT LPSWATEDTM TKLRELSELS LLSLYGIHKQ KEKSRLQGGV LVNEILNHMK RATQIPSYKK LIMYSAHDTT VSGLQMALDV YNGLLPPYAS CHLTELYFEK GEYFVEMYYR NETQHEPYPL MLPGCSPSCP LERFAELVGP VIPQDWSTEC MTTNSHQGTE DSTDHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Chuang TD., et al. (2010) J Biol Chem. 285:23598-23606. Taira A., et al. (2007) Oncology. 21:1003-1010. |
| Supplier | ARP |
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