| Product Name | ALKBH2 Polyclonal Antibody |
|---|---|
| Description | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. |
| Synonyms | ABH2 |
| Host | Rabbit |
| Immunogen | Recombinant protein of human ALKBH2 |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q6NS38 |
| Supplier | Elabscience |
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