| Product Name | AMIGO-1 Antibody |
|---|---|
| Description | The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction. . Mouse Anti-Human AMIGO-1 Monoclonal IgG1 |
| Synonyms | AMIGO 1 Antibody, AMIGO1 Antibody, Adhesion molecule with Ig like domain 1 Antibody, Amphoterin-induced protein 1 Antibody, Alivin-2 Antibody, Alivin 2 Antibody, Ali2 Antibody, AMIGO Antibody, KIAA1163 Antibody, Amphoterin induced gene and ORF (Amigo) Ant |
| Host | Mouse |
| Clone | S86-36 |
| Immunogen | Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1 |
| Isotype | IgG1 |
| Specificity | Detects ~60-80kDa depending on maturity/glycosylation. |
| Reactivity | Human, Mouse, Rat |
| Applications | ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_065754.2. 57463 |
| Uniprot | Q86WK6 |
| Supplier | Stressmarq Biosciences |
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