Anti-Alkaline Phosphatase Polyclonal Antibody

Antibodies, Polyclonal Antibodies
More Information
Product Name Anti-Alkaline Phosphatase Polyclonal Antibody
Description Rabbit IgG polyclonal antibody for Alkaline phosphatase, tissue-nonspecific isozyme(ALPL) detection. Tested with WB, IHC-P in Mouse, Rat.
Reactivity Predicted to work with: mouse, Reacts with: rat
Applications WB
Background Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. Liver/bone/kidney alkaline phosphatase, also known as tissue-nonspecific alkaline phosphatase, acts physiologically as a lipid-anchored phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP) ectophosphatase Mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.
Form Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Host Rabbit
Isotype Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of rat Alkaline Phosphatase(18-32aa, FVPEKEKDPSYWRQQ), different from the related mouse sequence by one amino acid.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity No cross reactivity with other proteins.
Synonyms Akp2 antibody, Alkaline phosphatase intestinal antibody, Alkaline phosphatase intestinal precursor antibody, Alkaline phosphatase liver/bone/kidney antibody, Alkaline phosphatase placental antibody, Alkaline phosphatase placental like 2 antibody, Alkaline phosphatase placental like antibody, Alkaline phosphatase placental type antibody, Alkaline phosphomonoesterase antibody, ALP 1 antibody, ALP antibody, ALP I antibody, ALP L antibody, ALP P antibody, ALPG antibody, ALPI antibody, ALPL antibody, ALPP antibody, ALPPL antibody, ALPPL2 antibody, AP TNAP antibody, FLJ40094 antibody, GCAP antibody, Germ cell alkaline phosphatase antibody, Glycerophosphatase antibody, HOPS antibody, IAP antibody, Intestinal alkaline phosphatase antibody, Kasahara isozyme antibody, Nagao isozyme antibody, OTTHUMP00000164357 antibody, Placental alkaline phosphatase antibody, Placental like alkaline phosphatase antibody, PLAP 1 antibody, PLAP antibody, PLAP like antibody, Regan isozyme antibody, Testicular and thymus alkaline phosphatase antibody, Tissue non specific alkaline phosphatase antibody, Tissue nonspecific ALP antibody, TNAP antibody, TNSALP antibody
Uniprot No. P08289

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