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|Product Name||Anti-ARF6 Polyclonal Antibody|
|Applications||ELISA, IHC, WB|
|Background||GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.|
|Form||Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.|
|Immunogen||Recombinant human ADP-ribosylation factor 6 protein (1-175AA)|
|Intended Use||For Research Use Only|
|Purification||Antigen Affinity Purified|
|Storage||Store at -20C or -80C. Avoid repeated freeze/thaw cycles.|
|Working Dilutions||WB: 1:500-2000, IHC: 1:20-1:200|
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