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|Product Name||Anti-BMP2 (clone AT15B3)|
|Description||BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.|
|Applications||Dot blot, ELISA, WB|
|Clone||Anti-human BMP2 mAb, clone AT15B3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BMP2 protein.|
|Form||Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.|
|Immunogen||Recombinant human BMP2 (283-396aa) purified from E. coli|
|References||Chen D., et al. (2004). Growth factors. 22(4):233-41 Schliephake H., et al. (2005). Clin Oral Implants Res. 17(6):666-72|
|Storage||Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Bone morphogenetic protein 2, BMP-2A, bmp2, Bone morphogenetic protein-2|
|Working Dilutions||Optimal dilution should be performed by user.|
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