Anti-CD31 / PECAM-1 (Endothelial Cell Marker), Monoclonal Antibody

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Product Name Anti-CD31 / PECAM-1 (Endothelial Cell Marker), Monoclonal Antibody
Description CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Applications FC, IF, IHC, WB
Clone JC/70A
Entrez ID 5175
FDA Status For Research Use Only
Form 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Gene ID 5175
Immunogen Membrane preparation of a spleen from a patient with hairy cell leukemia
Intended Use For Research Use Only
Isotype IgG1, kappa
Reactivity Human, Primate, Rabbit
References Parums DV et al. 1990. J Clin Pathol 43:752-757.
Muller WA, Kishimoto T, et al (eds) 1997. Leucocyte Typing VI, Garland Publishing Inc., New York and London, p 362-364. ISBN-13: 978-0815327455
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SwissProt P16284
Synonyms EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA'
Uniprot P16284
Host Mouse

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