| Product Name | Anti-Gastrin Polyclonal Antibody |
|---|---|
| Description | Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. |
| Synonyms | GAS, GAST |
| Immunogen | Synthetic human gastrin 1 conjugated to BSA |
| Specificity | The antibody can be used for the diagnosis of gastrin-producing tumors which are mainly found in the pancreas and occasionally in the stomach and the duodenum. Absorption with 10-100 ?g gastrin 1-34. gastrin 1-17, CCK 8 and CCK 4 per ml antiserum abolishes the staining, while CCK 10-20 does not. |
| Reactivity | Human, Rat |
| Applications | IF, IHC |
| Form | Serum containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| References | Mulder, H. et al. (1994) Gastroenterology 107 (3): 712-719Portela-Gomes G. et al. (1997) J. Histochem. & Cytochem. 45: 815-822 |
| Supplier | ARP |
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