Anti-Glial Fibrillary Acidic Protein (GFAP) Polyclonal Antibody
| Product Name | Anti-Glial Fibrillary Acidic Protein (GFAP) Polyclonal Antibody |
|---|---|
| Description | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| Synonyms | GFAP |
| Immunogen | Isolated from human spinal cord |
| Specificity | The antibody is directed against the 56 kDa GFAP protein, the main intermediate filament of glial cells and astrocytes. The antibody can be used to discriminate glial tumors, including astrocytomas and ependymomas from other tumors, as meningiomas, neuroblastomas, chordomas, chondrosarcomas, lymphomas and carcinomas. |
| Reactivity | Bovine, Human, Rat |
| Applications | IHC, WB |
| Form | Serum containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| References | Perentes, E. et al. (1987) Arch Path Lab Med 111: 796-812 |
| Supplier | ARP |
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