| Product Name | Anti-Human Hair Keratins Polyclonal Antibody |
|---|---|
| Description | Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human skin. It is also the key structural component of hair and nails. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and insoluble and form strong unmineralized tissues found in reptiles, birds, amphibians, and mammals. The only other biological matter known to approximate the toughness of keratinized tissue is chitin. |
| Immunogen | Synthetic peptides common to human type I (acidic) andtype II (basic) hair (trichocytic) keratins K31-K40 (formerdesignation hHa1-hHa8, Ka35 and Ka36):LESEDCKLPSNP-C; and K81-K86 (former designationhHb1-hHb4): VNVCVSSSRGGVV-C, both coupled to KLH |
| Specificity | The antiserum stains most prominently human hair keratins K81-K86 (type II) and considerably weaker K31-K40 (type I) hair keratins present in the hair cortex, hair cuticle and tumors derived therefrom. |
| Reactivity | Human, Mouse |
| Applications | IF, IHC, WB |
| Form | Stabilized Serum |
| Storage | 2-8C |
| References | Langbein L, Schweizer J (2005) Intern Rev Cytology 243: 1-78 |
| Supplier | ARP |
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