Anti-NANS (clone AT1G6)

Antibodies, Monoclonal Antibodies
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Product Name Anti-NANS (clone AT1G6)
Description NANS(Sialic acids synthease) is an enzyme that functions in the biosynthetic pathways of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone AT1G6. Anti-human NANS mAb, clone AT1G6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NANS protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Species Mouse
Host Mouse
Isotype IgG1, K
Immunogen Recombinant human NANS (1-359aa) purified from E. coli
Interest Fields Proteases & Inhibitors
NCBI Number NP_061819
References Milstein O., et al. (2008) J Biol Chem. 283(49):34414-22.Aldape MJ., et al. (2007) J Infect Dis. 195(12):1838-45.
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms Sialic acid synthase, SAS, N acetylneuraminate synthase
Working Dilutions Optimal dilution should be performed by user.

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