Anti-Vimentin Monoclonal Antibody

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Product Name Anti-Vimentin Monoclonal Antibody
Description This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. Mouse Monoclonal Antibody to Vimentin. Polypeptide reacting: MW 53,325 (pI 4.95) intermediate filament protein (vimentin) of Xenopus laevis (epitope presumably located between amino acids 79 and 88 within rod domain)
Background This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Clone XL-VIM-14.13
Isotype IgG1
Immunogen Vimentin from cytoskeletal fraction of XLKE cells (cultured Xenopus laevis kidney epithelial cells)
Synonyms VIM, RP11-124N14.1, CTRCT30
Specificity Vimentin of amphibia and fish, predominantly found in glial and white blood cells.
Reactivity Amphibian, Fish
Applications IHC, WB
Form Hybridoma culture supernatant
Storage 2-8C
References Herrmann, H. et al. (1996) J. Cell Sc 109: 569-578
Intended Use For Research Use Only
FDA Status For Research Use Only

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