APOM, 23-188aa, Human

Proteins, Recombinant
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Product Name APOM, 23-188aa, Human
Applications SDS-PAGE
Background Apolipoproteins are protein components of plasma lipoproteins. APOM is a member of the lipocalin family of proteins. APOM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. APOM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions. The concentration of APOM in plasma strongly correlates with total cholesterol. Low concentrations of APOM in plasma are associated with diabetes. Recombinant human APOM protein was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 22.0 kDa (194aa), confirmed by MALDI-TOF.
NCBI Accession # NP_061974
Purity > 90% by SDS-PAGE
References Jiang J., et al. (2008) Lipids Health Dis. 7:25.
Duan J., et al. (2001) FEBS Lett. 499(1-2):127-32.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms G3a, HSPC336, NG20, Apolipoprotein M Apo M, ApoM, G3A, MGC22400, NG20 like protein, Protein G3a.

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