Aprataxin, 1-168aa, Human

Proteins, Recombinant
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Product Name Aprataxin, 1-168aa, Human
Applications SDS-PAGE
Background Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 27.5 kDa (241aa), confirmed by MALDI-TOF.
NCBI Accession # NP_778241
Purity > 95% by SDS-PAGE
References Kijas A.W., et al (2006) J. Biol. Chem. 281:13939-13948
Rass U., et al. (2007) J. Biol. Chem. 282:9469-9474
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms APTX, AXA1, AOA, AOA 1, AOA1, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, AXA 1, EAOH, EOAHA, FHA HIT, FLJ20157, MGC1072, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein.

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