Aprataxin, 1-168aa, Human

Category: Proteins
Catalog
01-1782
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Product Name Aprataxin, 1-168aa, Human
Description Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms APTX, AXA1, AOA, AOA 1, AOA1, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, AXA 1, EAOH, EOAHA, FHA HIT, FLJ20157, MGC1072, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein.
Host E.coli
Molecular Weight 27.5 kDa (241aa), confirmed by MALDI-TOF.
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMQD PKMQVYKDEQ VVVIKDKYPK ARYHWLVLPW TSISSLKAVA REHLELLKHM HTVGEKVIVD FAGSSKLRFR LGYHAIPSMS HVHLHVISQD FDSPCLKNKK HWNSFNTEYF LESQAVIEMV QEAGRVTVRD GMPELLKLPL RCHECQQLLP SIPQLKEHLR KHWTQ
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Kijas A.W., et al (2006) J. Biol. Chem. 281:13939-13948
Rass U., et al. (2007) J. Biol. Chem. 282:9469-9474
Supplier ARP

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