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|Product Name||ARL2, 1-184aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGLLTILKKM KQKERELRLL MLGLDNAGKT TILKKFNGED IDTISPTLGF NIKTLEHRGF KLNIWDVGGQ KSLRSYWRNY FESTDGLIWV VDSADRQRMQ DCQRELQSLL VEERLAGATL LIFANKQDLP GALSSNAIRE ALELDSIRSH HWCIQGCSAV TGENLLPGID WLLDDISSRI FTAD|
|Background||ARL2 belongs to the ADP-ribosylation factor (ARF) family. This protein functions as a component of a secretory pathway that is involved in the Ca2-dependent release of acetylcholine. It plays a role in the folding of tubule proteins, thereby playing an important role in microtubule dynamics and cell cycle progression. Unlike other members of the ARF family, ARL2 does not act as an activator of the catalytic subunit of cholera toxin. Recombinant human ARL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||1.0 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||37.0 kDa (316aa), confirmed by MALDI-TOF|
|NCBI Accession #||AAM12602|
|Purity||> 90% by SDS-PAGE|
|References||Smith DF., et al. (2010) Mol Biochem Parasitol. 173(2):123-31.
Dumontet C., et al (2009) PLoS One. 4(10):e7478.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||ADP-ribosylation factor-like protein 2, ARFL2|
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