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|Product Name||ARL4A, 1-200aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGNGLSDQTS ILSNLPSFQS FHIVILGLDC AGKTTVLYRL QFNEFVNTVP TKGFNTEKIK VTLGNSKTVT FHFWDVGGQE KLRPLWKSYT RCTDGIVFVV DSVDVERMEE AKTELHKITR ISENQGVPVL IVANKQDLRN SLSLSEIEKL LAMGELSSST PWHLQPTCAI IGDGLKEGLE KLHDMIIKRR KMLRQQKKKR|
|Background||ARL4A, also known as ADP-ribosylation factor-like protein 4A, is a member of the ARF-like protein (ARL) subfamily of small GTPases. It is most closely related to ARL6 and ARL7. Unlike ARFs, ARL4 does not activate the cholera toxin ADP-ribosyltranferase. This protein may play a role in neurogenesis during embryonic development and somitogenesis in the early stages of adult spermatogenesis. Recombinant human ARL4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.|
|Intended Use||For Research Use Only|
|Molecular Weight||15.9 kDa (142aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_005729|
|Purity||> 90% by SDS-PAGE|
|References||Lin CY. et al. (2000) J. Biol. Chem. 275:37815-23.
Schurmann A. et al. (1994) J. Biol. Chem. 269: 15683-8.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||ADP-ribosylation factor-like protein 4A, ARL4|
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