ATOH1, 158-354aa, Human

Category: Proteins
Catalog
01-P1485
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Product Name ATOH1, 158-354aa, Human
Description ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Recombinant human ATOH1 protein was expressed in E.coli.
Synonyms Protein atonal homolog 1, ATH1, bHLHa14, HATH1, MATH-1
Host E.coli
Molecular Weight 11 kDa (104aa)
Amino Acid Sequence MKQRRLAANA RERRRMHGLN HAFDQLRNVI PSFNNDKKLS KYETLQMAQI YINALSELLQ TPSGGEQPPP PPASCKSDHH HLRTAASYEG GAGNATAAGA QQASGGSQRP TPPGSCRTRF SAPASAGGYS VQLDALHFST FEDSALTAMM AQKNLSPSLP GSILQPVQEE NSKTSPRSHR SDGEFSPHSH YSDSDEAS
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Ben-Arie N., et al. (1996) Hum. Mol. Genet. 5:1207-1216
The MGC Project Team (2004) Genome Res. 14:2121-2127
Supplier ARP

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