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|Product Name||ATP5H, 1-161aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMAGRKLA LKTIDWVAFA EIIPQNQKAI ASSLKSWNET LTSRLAALPE NPPAIDWAYY KANVAKAGLV DDFEKKFNAL KVPVPEDKYT AQVDAEEKED VKSCAEWVSL SKARIVEYEK EMEKMKNLIP FDQMTIEDLN EAFPETKLDK KKYPYWPHQP IENL|
|Background||ATP synthase subunit d, also known as ATP5H, is a 161 amino acid protein that belongs to the ATPase d subunit family. ATP5H encodes the d subunit of the F0 complex. ATP5H produces ATP from ADP in the presence of a proton gradient across the membrane, which is generated by electron transport complexes of the respiratory chain. Localizing to mitochondrial inner membrane, ATP5H exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 17q25.1. Recombinant human ATP5H protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT.|
|Intended Use||For Research Use Only|
|Molecular Weight||22 kDa (203aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_006347|
|Purity||> 85% by SDS-PAGE|
|References||Noh H S., et al. (2004) Brain Res. 129:80-87.
Sansanwal P., et al. (2010) J Am Soc Nephrol. 21:272-283.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||ATP synthase subunit d, mitochondrial isoform a, ATPQ|
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