BAALC, 1-145aa, Human

Proteins, Recombinant
More Information
Product Name BAALC, 1-145aa, Human
Background Brain and acute leukemia, cytoplasmic (BAALC) is localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKIIalpha and is thought to play a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant predict adverse clinical outcome and may define important risk factor in cytogenetically normal acute myeloid leukemia (AML). Recombinant human BAALC, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Synonyms , Brain and acute leukemia, cytoplasmic isoform 1 Brain and acute leukemia cytoplasmic, FLJ12015.
Host E.coli
Molecular Weight 36.5 kDa (325aa), confirmed by MALDI-TOF.
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 50mM NaCl, 10% glycerol
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_079088
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Tanner SM., et al. (2001) Proc Natl Acad Sci U S A. 98(24):13901-6.
Satoskar AA., et al. (2005) Gene Expr Patterns. 5(4):463-73.

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