BAG1, 1-230aa, Human

Proteins, Recombinant
More Information
Product Name BAG1, 1-230aa, Human
Background BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer's. It is localized to the cytosol, nucleus or both. Recombinant human BAG1 was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Synonyms HAP, RAP46, BCL2-associated athanogene 1 Bag 1, BAG family molecular chaperone regulator 1, BCL 2 associated athanogene, BCL 2 Associated Athanogene 1, BCL 2 binding athanogene 1, BCL2 associated athanogene, BCL2 associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP1, Haptoglobin, RAP 46.
Host E.coli
Molecular Weight 29.5 kDa (260aa), confirmed by MALDI-TOF.
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_001165886
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Wang HG., et al. (1996) Proc Natl Acad Sci U S A. 93(14):7063-8.
Takayama S., et al. (1995) Cell. 80(2):279-84.

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