BID, 1-195aa, Human, Recombinant

Proteins, Recombinant
Questions? Contact Us
More Information
Product Name BID, 1-195aa, Human, Recombinant
Applications SDS-PAGE
Background BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 64.8 kDa (563aa)
NCBI Accession # NP_001187
Purity > 95% by SDS-PAGE
References Luo, X., et al. (1998). Cell. 94:481
Li, H., et al. (1998). Cell. 94:491
Zha, J., et al. (2000). Science 290:1761
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms FP497, MGC15319, MGC42355, BH3 interacting domain death agonist isoform 2, BID, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist, Apoptotic death agonist BID, BH3 interacting domain death agonist, HGNC:1050, BH3 interacting domain death agonist p11, BH3 interacting domain death agonist p13, BH3 interacting domain death agonist p15, BID isoform ES(1b), BID isoform L(2), Desmocollin type 4, Human BID coding sequence, OTTHUMP00000196197, p11 BID, p13 BID, p15 BID, p22 BID.
Tag His-tag

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.

Customers Also Viewed
  1. ACTA2, 3-377aa, Human
    ACTA2, 3-377aa, Human
  2. Anti-PDCD4 (clone k4C1)
    Anti-PDCD4 (clone k4C1)
    Programmed cell deat...
  3. IL-6 Human ELISA Kit
    IL-6 Human ELISA Kit
    This kit is for the ...

Hi, have questions?

An ARP Customer Service Representative is happy to help!

or Call (800) 832-2611