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|Product Name||Biliverdin reductase B, 1-206aa, Human, Recombinant|
|Amino Acid Sequence||MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ|
|Background||Biliverdin reductase B (BLVRB) is an enzyme (EC 188.8.131.52) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris pH 8.0, 5mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||21 kDa (190 aa)|
|NCBI Accession #||NP_000704.1|
|Purity||> 95% by SDS-PAGE|
|References||L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400
Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 99(25):16093-8
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||BLVRB, FLR, BVRB, SDR43U1, MGC117413, Biliverdin reductase B, Biliverdin IX beta reductase, BVR B, Flavin reductase, Flavin reductase (NADPH), FR, GHBP, Green heme binding protein, MGC117413, NADPH dependent diaphorase, NADPH flavin reductase.|
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