| Product Name | BK Beta 3a Antibody : ATTO 390 |
|---|---|
| Description | BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release (1). A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia (2). This has major implications on other physiological processes in tissues other than the brain. Mouse Anti-Mouse BK Beta3a Monoclonal IgG1 |
| Synonyms | HBETA3 Antibody, KCNMB2 Antibody, KCNMBL Antibody, BKBeta3 Antibody, KCNMB3 Antibody, Calcium-activated potassium channel subunit beta-3 Antibody, BK channel subunit beta-3 Antibody, BKbeta3 Antibody, Hbeta3 Antibody, Calcium-activated potassium channel A |
| Host | Mouse |
| Clone | S40B-18 |
| Immunogen | Fusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a |
| Isotype | IgG1 |
| Specificity | Detects ~32 kDa. No cross-reactivity against BKBeta1, BKBeta2, BKBeta3b or BKBeta4. |
| Reactivity | Human, Mouse, Rat |
| Applications | AM, ICC, IF, IHC, IP, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_055222.3. 27094 |
| Uniprot | Q9NPA1 |
| Supplier | Stressmarq Biosciences |
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