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|Product Name||CAPS, 1-189aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MDAVDATMEK LRAQCLSRGA SGIQGLARFF RQLDRDGSRS LDADEFRQGL AKLGLVLDQA EAEGVCRKWD RNGSGTLDLE EFLRALRPPM SQAREAVIAA AFAKLDRSGD GVVTVDDLRG VYSGRAHPKV RSGEWTEDEV LRRFLDNFDS SEKDGQVTLA EFQDYYSGVS ASMNTDEEFV AMMTSAWQL|
|Background||Calcyphosine, also known as CAPS, is a calcium-binding protein containing four EF-hand domains. CAPS is initially identified as thyroid protein p24 that is found in several epithelium and in some cells of the central nervous system. It may play a role in the regulation of ion transport. In thyroid follicular cells, CAPS is synthesized and phosphorylated in response to stimulation by thyrotropin and cAMP agonists. Recombinant human CAPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||12.9 kDa (112aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_004049|
|Purity||> 95% by SDS-PAGE|
|References||El Housni H, et al. (1997) Mol Cell Endocrinol. 135(1):93-7.
Halleux P, et al. (1998) J Chem Neuroanat. 15(4):239-50.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Calcyphosine, CAPS1, Calcyphosin|
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