Cat Troponin I, cardiac muscle (TNNI3) ELISA Kit

Category: Assay Kits
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AE13918CA
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Product Name Cat Troponin I, cardiac muscle (TNNI3) ELISA Kit
Description Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Equally reactive with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components. (In the presence of 5 mM EDTA). Antibodies are not affected by heparin, phosphorylation, oxidation and troponin complex formation. No cross-reaction with skeletal muscle troponin I. This assay has high sensitivity and excellent specificity for detection of Cat TNNI3. No significant cross-reactivity or interference between Cat TNNI3 and analogues was observed.
Synonyms CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI, familial hypertrophic cardiomyopathy 7|troponin I, cardiac
Method Sandwich ELISA
Detection Range 2.34-150 ng/mL
Sensitivity 0.65 ng/mL
Reactivity Feline
Sample Types Serum, Plasma, Other biological fluids.
Supplier Abebio

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