CD44 [BU75] Monoclonal Antibody

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Product Name CD44 [BU75] Monoclonal Antibody
Description The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Background The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Host Mouse
Clone BU75
Isotype IgG2a
Immunogen Folicual dentritic cells and germinal centre B cells
Synonyms HCAM, homing cell adhesion molecule, Pgp-1, phagocytic glycoprotein-1, Hermes antigen, lymphocyte homing receptor, ECM-III, HUTCH-1.
Target CD44
Reactivity Human
Applications FACS, IF, IHC, IP, WB
Intended Use For Research Use Only

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