CD45 Antibody: Streptavidin

Category: Antibodies
Catalog
SMC-256D-STR
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Product Name CD45 Antibody: Streptavidin
Description CD45 is a 180-240 kD glycoprotein, also known as the leukocyte common antigen (LCA), T200 or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, broadly expressed amount hematopoietic cells. There are kmultiple isoforms of CD45 distributed throughout the immune system, and they arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell, as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. Mouse Anti-Human CD45 Monoclonal IgG1 
Synonyms B220 Antibody, CD 45 Antibody, CD45R Antibody, GP180 Antibody, LCA Antibody, Protein tyrosine phosphatase receptor type c polypeptide Antibody, PTPRC_HUMAN Antibody, T200 glycoprotein Antibody

Host Mouse
Clone 12A9
Immunogen Purified recombinant fragment of human CD45 expressed in E. Coli
Isotype IgG1 
Specificity Detects endogenous CD45 proteins. (~147KD).
Reactivity Human
Applications IHC, WB
Form Purified, in PBS (without Mg2+ and Ca2+), 50% glycerol, pH 7.4, 150mM NaCl, 0.02% sodium azide
Gene Id NP_563578.2. 5788
Uniprot P08575
Supplier Stressmarq Biosciences

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